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ubiquinol-8 biosynthesis (early decarboxylation)

State Icon Reaction EC-Number Confidence maximal confidence score from EnzymeDetector
2-methoxy-6-(all-trans-octaprenyl)phenol + O2 + NADPH + H+ <=> 2-methoxy-6-octaprenyl-1,4-benzoquinol + H2O + NADP+ 1.14.13.M56

S-adenosyl-L-methionine + 2-octaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinone <=> H+ + ubiquinol-8 + S-adenosyl-L-homocysteine 2.1.1.64 3-demethylubiquinol 3-O-methyltransferase

octaprenyl_diphosphate + 4-hydroxybenzoate <=> 4-hydroxy-3-octaprenylbenzoate + diphosphate 2.5.1.39 4-hydroxybenzoate polyprenyltransferase

S-adenosyl-L-methionine + 2-methoxy-6-octaprenyl-1,4-benzoquinol <=> H+ + S-adenosyl-L-homocysteine + 6-methoxy-3-methyl-2-all-trans-octaprenyl-1,4-benzoquinol 2.1.1.201 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase

6-methoxy-3-methyl-2-all-trans-octaprenyl-1,4-benzoquinol + O2 + reduced_acceptor <=> 2-octaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinone + H2O + acceptor 1.14.99.60 3-demethoxyubiquinol 3-hydroxylase

2-octaprenylphenol + O2 + NADPH + H+ <=> 3-(all-trans-octaprenyl)benzene-1,2-diol + H2O + NADP+ 1.14.13.240 2-polyprenylphenol 6-hydroxylase

S-adenosyl-L-methionine + 3-(all-trans-octaprenyl)benzene-1,2-diol <=> H+ + 2-methoxy-6-(all-trans-octaprenyl)phenol + S-adenosyl-L-homocysteine 2.1.1.222 2-polyprenyl-6-hydroxyphenol methylase

H+ + 4-hydroxy-3-octaprenylbenzoate <=> 2-octaprenylphenol + CO2 4.1.1.98 4-hydroxy-3-polyprenylbenzoate decarboxylase

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